A study with 2,400 broilers was carried out to compare the effect of the use of mannanoligosaccharides, Saccharomyces cerevisiae cell wall or growth promoter (Olaquindox) in the diet on broiler. Diets were based on corn and soybean meal. A completely randomized experimental design was used, and the obtained data were evaluated by analysis of variance and test of Tukey at a level of 5%. The following parameters were measured: feed intake, daily weight gain, feed conversion ratio, and mortality. It was concluded that the effect of the inclusion of mannanoligosaccharides in the diet on the studied parameters was significantly higher as compared to the inclusion of cell wall or to the control diet, but the effect was not different as compared to the inclusion of growth promoter.